Isobaric tags for relative and absolute quantitation labeling coupled with 2D-LC MS/MS proteomics analysis of anterior insula in morphine induced place preference rats with high frequency deep brain stimulation intervention

ABSTRACT: The rats were implanted bilaterally with electrodes in anterior insula and then trained to morphine conditioned place preference and chronic high frequency electrical stimulation was applied during the withdrawal phase. Proteomics analysis of the rat anterior insula was performed using isobaric tags for relative and absolute quantitation labeling (iTRAQ) coupled with 2D-LC MS/MS

ORGANISM(S): Rattus Rattus

SUBMITTER: Wang Feng  

PROVIDER: PXD021122 | iProX | Tue Aug 25 00:00:00 BST 2020

REPOSITORIES: iProX