Dataset Information
Head and neck cancer cells label free proteomics
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Liang Zhou
PROVIDER: PXD021532 | iProX | Thu Sep 17 00:00:00 BST 2020
REPOSITORIES: iProX
Publications
Eukaryotic translation initiation factor 3 subunit B promotes head and neck cancer via CEBPB translation.
Cancer cell international 20220422 1
<h4>Background</h4>Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer type worldwide. Deregulation of mRNA translation is a frequent feature of cancer. Eukaryotic translation initiation factor 3 subunit B (EIF3B) has been reported as an oncogene; however, its role in HNSCC has yet to be fully elucidated.<h4>Methods</h4>In this study, the clinical significance of EIF3B expression was analyzed based on TCGA datasets. Then, EIF3B expression was knocked down and its role i ...[more]
