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The LC-MS/MS data of EVs derived from Talaromyces marneffei

ABSTRACT: Our experiment showed that the immunostimulatory effect of EVs derived from Talaromyces marneffei(TM) was significantly weaken with protease pretreatment, but not in pretreatment with dsDNA and RNase A hydrolase. To further investigate its protein composition, EVs derived from TM were further analyzed by LS-MS

ORGANISM(S): Talaromyces Marneffei

SUBMITTER: Xiumei Hu

PROVIDER: PXD022162 | iProX | Mon Oct 26 00:00:00 GMT 2020

REPOSITORIES: iProX

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Extracellular Vesicles Derived From Talaromyces marneffei Yeasts Mediate Inflammatory Response in Macrophage Cells by Bioactive Protein Components.

Yang Biao B Wang Jingyu J Jiang Hongye H Lin Huixian H Ou Zihao Z Ullah Amir A Hua Yuneng Y Chen Juanjiang J Lin Xiaomin X Hu Xiumei X Zheng Lei L Wang Qian Q

Frontiers in microbiology 20210108

Extracellular vesicles (EVs) loaded with proteins, nucleic acids, membrane lipids, and other virulence factors could participate in pathogenic processes in some fungi such as Cryptococcus neoformans and Candida albicans. However, the specific characteristics of EVs derived from Talaromyces marneffei (TM) still have not been figured out yet. In the present study, it has been observed that TM-derived EVs were a heterogeneous group of nanosized membrane vesicles (30-300 nm) und ...[more]

PMID: 33488545

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