Dataset Information
Human iTRAQ biological information analysis
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Qixiao Zhai
PROVIDER: PXD022209 | iProX | Wed Oct 28 00:00:00 GMT 2020
REPOSITORIES: iProX
Publications
TOP2A deficit-induced abnormal decidualization leads to recurrent implantation failure via the NF-κB signaling pathway.
Reproductive biology and endocrinology : RB&E 20220922 1
<h4>Background</h4>Successful implantation is a complex process that is influenced by embryo quality, endometrial receptivity, immune factors, and the specific type of in vitro fertilization protocol used. DNA topoisomerase IIα (TOP2A) is a well-known protein involved in cell proliferation; however, its expression and effect on the endometrium in recurrent implantation failure (RIF) have not been fully elucidated.<h4>Methods</h4>The human endometrial tissues of healthy controls and patients with ...[more]
