A Metabolite Triplet in Serum Improves the Diagnostic Accuracy of Prediabetes and Diabetes Screening
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ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Guowang Xu
PROVIDER: PXD022801 | iProX | Mon Nov 30 00:00:00 GMT 2020
REPOSITORIES: iProX
Publications
Metabolite Triplet in Serum Improves the Diagnostic Accuracy of Prediabetes and Diabetes Screening.
Wang Lichao L Zhang Yinan Y Liu Xinyu X Zhao Xinjie X Ouyang Yang Y Qiu Gaokun G Lv Wangjie W Zheng Fujian F Wang QingQing Q Lu Xin X Peng Xiaojun X Wu Tangchun T Lehmann Rainer R Wang Congrong C Jia Weiping W Xu Guowang G
Journal of proteome research 20201221 1
Large-scale population screenings are not feasible by applying laborious oral glucose tolerance tests, but using fasting blood glucose (FPG) and glycated hemoglobin (HbA<sub>1c</sub>), a considerable number of diagnoses are missed. A novel marker is urgently needed to improve the diagnostic accuracy of broad-scale diabetes screening in easy-to-collect blood samples. In this study, by applying a novel knowledge-based, multistage discovery and validation strategy, we scaled down from 108 diabetes- ...[more]
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