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Molecular Phenomics of the Gut Ecosystem in COVID-19 Patients

ABSTRACT: Stool metaproteomics of COVID-19 patients and healthy subjects to discover host and microbial protein alterations of gut ecosystem.

ORGANISM(S): Homo Sapiens

SUBMITTER: Zhixiang Yan

PROVIDER: PXD023099 | iProX | Mon Dec 14 00:00:00 GMT 2020

REPOSITORIES: iProX

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Fecal multi-omics analysis reveals diverse molecular alterations of gut ecosystem in COVID-19 patients.

He Feixiang F Zhang Ting T Xue Kewen K Fang Zhaoxiong Z Jiang Guanmin G Huang Siwen S Li Kexue K Gu Zhiqiang Z Shi Honggang H Zhang Zhenyi Z Zhu Huijin H Lin Lu L Li Jialin J Xiao Fei F Shan Hong H Yan Ru R Li Xiaofeng X Yan Zhixiang Z

Analytica chimica acta 20210726

Gut ecosystem has profound effects on host physiology and health. Gastrointestinal (GI) symptoms were frequently observed in patients with COVID-19. Compared with other organs, gut antiviral response can result in more complicated immune responses because of the interactions between the gut microbiota and host immunity. However, there are still large knowledge gaps in the impact of COVID-19 on gut molecular profiles and commensal microbiome, hindering our comprehensive understanding of the patho ...[more]

PMID: 34538334

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