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Proteomics analysis reveals the effect of Aeromonas hydrophila sirtuin CobB on biological functions

ABSTRACT: a DIA-based proteomics method was used to compare the differently protein abundance between cobB deleted mutant and wild type strain.

ORGANISM(S): Aeromonas Hydrophila 07-345-3437

SUBMITTER: Lin Xiangmin

PROVIDER: PXD023330 | iProX | Thu Dec 31 00:00:00 GMT 2020

REPOSITORIES: iProX

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Proteomics analysis reveals the effect of Aeromonas hydrophila sirtuin CobB on biological functions.

Wang Guibin G Wang Yuqian Y Zhang Lishan L Cai Qilan Q Lin Yuexu Y Lin Ling L Lin Xiangmin X

Journal of proteomics 20200530

Our previous studies have profiled lysine acetylation and succinylation modifications in Aeromonas hydrophila protein and have found that CobB may be involved in lysine deacylation; however, its effects on bacterial biological function are still unknown. In this study, a data-independent acquisition (DIA)-based proteomics method was used to compare the protein abundance between cob-deleted mutants and wild-type strains. Of the total 2385 identified proteins, 385 were found to have increased abun ...[more]

PMID: 32480081

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