Caspofungin-induced Responses in the Planktonic Cells and Biofilms of Candida albicans
Ontology highlight
ABSTRACT:
ORGANISM(S): Candida Albicans
SUBMITTER: 
Prof. Lijian Jin
PROVIDER: PXD023480 | iProX | Fri Jan 08 00:00:00 GMT 2021
REPOSITORIES: iProX
Publications
Proteomic Analysis of Caspofungin-Induced Responses in Planktonic Cells and Biofilms of <i>Candida albicans</i>.
Li Peng P Seneviratne Chaminda J CJ Luan Qingxian Q Jin Lijian L
Frontiers in microbiology 20210218
<i>Candida albicans</i> biofilms display markedly increased antifungal resistance, and the underlying mechanisms remain unclear. This study investigated the signature profiles of <i>C. albicans</i> planktonic cells and biofilms in response to caspofungin (CAS) by mass spectrometry-based shotgun proteomics. We found that <i>C. albicans</i> biofilms were twofold more resistant to CAS with reference to planktonic cells. Notably, 9.6% of <i>C. albicans</i> biofilm cells survived the lethal treatment ...[more]
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