Ontology highlight
ABSTRACT:
ORGANISM(S): Mus Musculus
SUBMITTER: Hua Zhang
PROVIDER: PXD024931 | iProX | Tue Mar 23 00:00:00 GMT 2021
REPOSITORIES: iProX
Zhang Yan Y Wang Ye Y Feng Xie'an X Zhang Shuo S Xu Xueqiang X Li Lingyu L Niu Shudong S Bo Yingnan Y Wang Chao C Li Zhen Z Xia Guoliang G Zhang Hua H
Nature communications 20210505 1
Crosstalk between oocytes and surrounding somatic cells is crucial for mammalian oogenesis, but the structural mechanisms on oocytes to control female reproduction remain unknown. Here we combine endogenous-fluorescent tracing mouse models with a high-resolution live-cell imaging system to characterize oocyte-derived mushroom-like microvilli (Oo-Mvi), which mediate germ-somatic communication in mice. We perform 3D live-cell imaging to show that Oo-Mvi exhibit cellular characteristics that fit an ...[more]