Comprehensive iTRAQ based proteomic Characterization of Coronary Artery Diseases
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ABSTRACT: Coronary artery disease (CAD) remains a leading cause of mortality worldwide. The current clinical diagnosis differentiates among the types of CAD mainly dependents on coronary angiography. High cost limit it to a select population. On one hand, a sizable portion of individuals who underwent invasive angiography had been shown to have normal coronary arteries. On the other hand, episodes of myocardial ischemia or infarction are possible after atypical symptoms in some patients with CAD, especially in patients who are elderly or have diabetes. Additionally, the transition from coronary stability to instability is less well understood. To identify the marker proteins for CAD progression, proteomic technique was applied.
ORGANISM(S): Homo Sapiens
SUBMITTER: Lian-Wen Qi
PROVIDER: PXD025017 | iProX | Wed Apr 04 00:00:00 BST 2018
REPOSITORIES: iProX
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