Ontology highlight
ABSTRACT:
ORGANISM(S): Arabidopsis Thaliana
SUBMITTER: Zhaobo Lang
PROVIDER: PXD025147 | iProX | Thu Apr 01 00:00:00 BST 2021
REPOSITORIES: iProX
Niu Qingfeng Q Song Zhe Z Tang Kai K Chen Lixian L Wang Lisi L Ban Ting T Guo Zhongxin Z Kim Chanhong C Zhang Heng H Duan Cheng-Guo CG Zhang Huiming H Zhu Jian-Kang JK Du Jiamu J Lang Zhaobo Z
Nature communications 20210607 1
In plants, RNA-directed DNA methylation (RdDM) is a well-known de novo DNA methylation pathway that involves two plant-specific RNA polymerases, Pol IV and Pol V. In this study, we discovered and characterized an RdDM factor, RDM15. Through DNA methylome and genome-wide siRNA analyses, we show that RDM15 is required for RdDM-dependent DNA methylation and siRNA accumulation at a subset of RdDM target loci. We show that RDM15 contributes to Pol V-dependent downstream siRNA accumulation and interac ...[more]