Proteomics

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The multiomics landscape of serum exosomes during the development of sepsis


ABSTRACT: Our study describes the landscape of the molecular dynamics of serum exosomes during the development of sepsis and proposes some hypothetical molecular mechanisms, which may provide helpful diagnostic and therapeutic insights for the ongoing battle against sepsis.

ORGANISM(S): Homo Sapiens

SUBMITTER: Yong Jiang  

PROVIDER: PXD025311 | iProX | Sun Apr 11 00:00:00 BST 2021

REPOSITORIES: iProX

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<h4>Introduction</h4>Sepsis is an infection-induced severe inflammatory disorder leading to multiple organ dysfunction. It remains a highly lethal condition for which early diagnosis and therapy achieve unsatisfactory results. Circulating exosomes containing biomarkers and mediators of sepsis have recently received attention, but the progress has been far from optimal.<h4>Objectives</h4>The present study focuses on the profiles of molecular dynamics in serum exosomes and explores the potential m  ...[more]

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