Dataset Information
Protein interaction network reveals the biofunctional difference between vegetative cell and heterocyst in multicellular cyanobacteria
Ontology highlight
ABSTRACT:
ORGANISM(S): Nostoc Sp. Pcc 7120 = Fachb-418
SUBMITTER: 
Cuihong Wan
PROVIDER: PXD025312 | iProX | Tue Apr 26 00:00:00 BST 2022
REPOSITORIES: iProX
Publications
Comparative Network Biology Discovers Protein Complexes That Underline Cellular Differentiation in Anabaena sp.
Molecular & cellular proteomics : MCP 20220311 4
The filamentous cyanobacterium Anabaena sp. PCC 7120 can differentiate into heterocysts to fix atmospheric nitrogen. During cell differentiation, cellular morphology and gene expression undergo a series of significant changes. To uncover the mechanisms responsible for these alterations, we built protein-protein interaction (PPI) networks for these two cell types by cofractionation coupled with mass spectrometry. We predicted 280 and 215 protein complexes, with 6322 and 2791 high-confidence PPIs ...[more]
