Rat heterotopic ossification model proteome

ABSTRACT: The mechanism of heterotopic ossification remains largely unclarified. in this project, we administrated Achilles tenotomy (AT) and partial Achilles tenotomy (PAT) to rat models to simulate the varied size of ectopic bone we observed in the clinical courses. Then we applied Data-independent acquisition (DIA) proteomic strategy to identify the proteins and signaling pathways associated with the progress of heterotopic ossification and propagation of the ectopic bone mass.

ORGANISM(S): Rattus Norvegicus

SUBMITTER: Biao Zhong  

PROVIDER: PXD025678 | iProX | Wed Apr 28 00:00:00 BST 2021

REPOSITORIES: iProX