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Quantitative proteomics of plasma and liver reveals the mechanism of turmeric in preventing hyperlipidemia in mice

ABSTRACT: TMT-based proteomic analysis was conducted for plasma and liver of C57BL/6J mouse model.

ORGANISM(S): Mus Musculus

SUBMITTER: Zhifeng Du

PROVIDER: PXD026108 | iProX | Wed May 19 00:00:00 BST 2021

REPOSITORIES: iProX

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Quantitative proteomics of plasma and liver reveals the mechanism of turmeric in preventing hyperlipidemia in mice.

Wang Meiqin M Wang Runjing R Li Lieyao L Yan Yingfei Y Jia Shuailong S Jiang Hongliang H Du Zhifeng Z

Food & function 20211101 21

Hyperlipidemia is manifested by abnormal levels of circulating lipids and may lead to various cardiovascular diseases. Studies have demonstrated that turmeric supplemented in food can effectively prevent hyperlipidemia. The aim of this study is to elucidate the underlying mechanism. 27 male C57BL/6J mice were randomly divided into three groups, which were fed with a standard diet, a high-fat diet and a high-fat diet supplemented with turmeric powder (2.0% w/w), respectively. After eight weeks of ...[more]

PMID: 34555841

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