Proteomics

Dataset Information

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Application of proteomics to investigation on infectious diseases of livestock and poultry


ABSTRACT: Proteomics are widely utilized to investigate growth, breeding, nutrition, and diseases of livestock and poultry. The effects of infections on abundance, post-translational modification, and interactions of host cell proteins have been systematically studied using proteomics methods, such as isoelectric focusing, two-dimensional electrophoresis, and mass spectrometry. The research will increase our understanding of pathogenesis of viral infection and contribute to development of novel anti-viral drugs for the livestock and poultry industries.

ORGANISM(S): Sus Scrofa Domesticus

SUBMITTER: Rui Li  

PROVIDER: PXD026209 | iProX | Sun May 23 00:00:00 BST 2021

REPOSITORIES: iProX

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Publications

Proteomic Investigation Reveals Eukaryotic Translation Initiation Factor 5A Involvement in Porcine Reproductive and Respiratory Syndrome Virus Infection <i>in vitro</i>.

Li Huawei H   Wan Bo B   Jiang Dawei D   Ji Pengchao P   Zhao Mengmeng M   Li Xinfeng X   Li Rui R   Qiao Songlin S  

Frontiers in veterinary science 20220413


Porcine reproductive and respiratory syndrome virus (PRRSV), one of the most serious animal pathogens in the world, has caused enormous global swine industry losses. An in-depth investigation of the PRRSV-host interaction would be beneficial for preventing and controlling PRRSV infections and transmission. In this study, we performed label-free quantitative proteomic assays to investigate proteome dynamics of porcine alveolar macrophages (PAMs) during infection with highly pathogenic PRRSV (HP-P  ...[more]

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