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Proteomic analysis of Fuzi and its processed products in treating Yang Deficiency Rats

ABSTRACT: The model rats of Yang deficiency syndrome were established by gavage of Huanglian and Dahuang and exhaustive swimming. The rats were treated with Fuzi, Yinfupian and Yangfupian. The liver tissue proteins were extracted and analyzed by TMT proteomics.

ORGANISM(S): Rattus Norvegicus

SUBMITTER: Lingyun Zhong

PROVIDER: PXD026321 | iProX | Thu May 27 00:00:00 BST 2021

REPOSITORIES: iProX

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Components and Pharmacodynamical Mechanism of Yinfupian Based on Liquid Chromatography-Mass Spectrometry and Proteomics Analyses.

Tong Heng-Li HL Chen Hao H Gong Fei-Peng FP Zhong Ling-Yun LY Zhu Jing J Yang Song-Hong SH

Frontiers in pharmacology 20210628

Objective: According to the treatment records of Yang deficiency syndrome (YDS) with characteristic decoction pieces of lateral root of Aconitum carmichaelii-Yinfupian (YF) in traditional Chinese medicine prepare school, known as "Jianchangbang". The aim of this study was to investigate differences in the composition and therapeutic mechanism of the unprocessed lateral root of Aconitum carmichaelii (ULRA) and its processed product (YF). Methods: Ultra-performance liqu ...[more]

PMID: 34262452

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