Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens Mus Musculus
SUBMITTER: Chen Ding
PROVIDER: PXD026362 | iProX | Sun May 30 00:00:00 BST 2021
REPOSITORIES: iProX
Bai Lin L Yang Guojian G Qin Zhaoyu Z Lyu Jiacheng J Wang Yunzhi Y Feng Jinwen J Liu Mingwei M Gong Tongqing T Li Xianju X Li Zhengyang Z Li Jixi J Qin Jun J Yang Wenjun W Ding Chen C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 20210805 19
DNA modifications, represented by 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC), play important roles in epigenetic regulation of biological processes. The specific recognition of DNA modifications by the transcriptional protein machinery is thought to be a potential mechanism for epigenetic-driven gene regulation, and many modified DNA-specific binding proteins have been uncovered. However, the panoramic view of the roles of DNA mo ...[more]