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N-terminomic Analysis of Mycobacterium tuberculosis H37Rv

ABSTRACT: Mycobacterium tuberculosis (MTB) is a species of pathogenic bacteria and the causative agent of tuberculosis. The type strain H37Rv has been sequenced in 1998, while many previous studies found its predicted genes exhibit frequent errors, particularly in start codons. Here, we applied a TMPP [(N-Succinimidyloxycarbonylmethyl) tris (2,4,6-trimethoxyphenyl) phosphonium bromide] labeling combined with StageTip separating strategy to characterize the N-terminal peptides. We identified 2,598 annotated proteins, which 1,078 proteins were labeled by TMPP.

ORGANISM(S): Mycobacterium Tuberculosis H37rv

SUBMITTER: Prof. Ping Xu

PROVIDER: PXD026846 | iProX | Fri Jun 18 00:00:00 BST 2021

REPOSITORIES: iProX

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