Dataset Information
Comprehensive mass spectrometry strategy for developing proteomic biomarkers of intracranial aneurysms
Ontology highlight
ABSTRACT:
ORGANISM(S): Oryctolagus Cuniculus Homo Sapiens
SUBMITTER: 
Pengyuan Yang
PROVIDER: PXD027116 | iProX | Mon Jul 05 00:00:00 BST 2021
REPOSITORIES: iProX
Publications
Comprehensive mass spectrometry for development of proteomic biomarkers of intracranial aneurysms.
Talanta 20211220
Protein biomarkers of intracranial aneurysm (IA) are essential for early detection and prediction of its rupture to facilitate the diagnosis and clinical management of the disease, monitor treatment response and detect recurrence. Here, we developed a comprehensive strategy for IA biomarker discovery by analyzing tissues from an animal model (n = 4) and serum from human patients (n = 60) using isobaric tandem mass tags-based quantitative proteomics. A total of 4811 and 562 proteins were identifi ...[more]
