Proteome characterization of glaucoma aqueous humour

ABSTRACT: This work describes a proteomic analysis for different types of glaucoma (PACG, NVG) and age-related cataract as control. The AH samples were recruited from 175 individual patients with PACG, NVG and age-related cataract. First, in discovery cohort the AH proteome characteristics of PAACG, PCACG and NVG with cataract were compared by DIA approach. Second, AH proteomic features of three types of glaucoma, PAACG, PCACG and NVG, were mutually compared. In validation cohort the key proteins of above comparison were validated by PRM approach.

ORGANISM(S): Homo Sapiens

SUBMITTER: Wei Sun  

PROVIDER: PXD027686 | iProX | Mon Aug 02 00:00:00 GMT+01:00 2021

REPOSITORIES: iProX