Shuangxinfang in Rats with Depression-behavior post Acute Myocardial Infarction from Proteomics

ABSTRACT: AMI models were established and PCF was administered in rats. Subjects were then assessed in an open field test recapitulating symptoms of depression. Afterward, pharmacoproteomic profiling of the hippocampus and peri-infarct border zone (BZ) was performed using a label-free liquid chromatography-tandem mass spectrometry (LC-MS/MS) technique, to identify contributing proteins and pathways responsible for myocardial ischemia and behavioral allostasis.

ORGANISM(S): Rattus Norvegicus

SUBMITTER: Zheyi Wang  

PROVIDER: PXD027832 | iProX | Tue Aug 10 00:00:00 BST 2021

REPOSITORIES: iProX