Proteomics

Dataset Information

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Proteome data of snake venoms_file 11


ABSTRACT: Proteome data of venomous snake profiled using liquid chromatography tandem mass spectrometry (LCMS/MS)

ORGANISM(S): Naja Nivea

SUBMITTER: Choo Hock Tan  

PROVIDER: PXD028220 | iProX | Tue Sep 07 00:00:00 BST 2021

REPOSITORIES: iProX

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Publications

Snake Venomics and Antivenomics of Cape Cobra (<i>Naja nivea</i>) from South Africa: Insights into Venom Toxicity and Cross-Neutralization Activity.

Tan Choo Hock CH   Wong Kin Ying KY   Huang Li-Kun LK   Tan Kae Yi KY   Tan Nget Hong NH   Wu Wen-Guey WG  

Toxins 20221207 12


<i>Naja nivea</i> (Cape Cobra) is endemic to southern Africa. Envenoming by <i>N. nivea</i> is neurotoxic, resulting in fatal paralysis. Its venom composition, however, has not been studied in depth, and specific antivenoms against it remain limited in supply. Applying a protein decomplexation approach, this study unveiled the venom proteome of <i>N. nivea</i> from South Africa. The major components in the venom are cytotoxins/cardiotoxins (~75.6% of total venom proteins) and alpha-neurotoxins (  ...[more]

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