Improving identification of lysine acetylated peptides using molecularly imprinted monolith prepared by a deep eutectic solvents monomer

ABSTRACT: A novel approach based on molecularly imprinted polymer (MIP) was developed to improve the extraction capacity of lysine acetylation peptide in real sample. Green deep eutectic solvents (DESs) were introduced and used as one of synergistic functional monomers with zinc acrylate (ZnA). Glycine-glycine-alanine-lysine(ac)-arginine (GGAKacR) was chosen as template, and N, N'-methylenbisacrylamide (MBAA) was used as cross-linker. The obtained GGAKacR-MIP had excellent selectivity for the template with imprinting factor up to 21.4.

ORGANISM(S): Mus Musculus

SUBMITTER: Zhaosheng Liu  

PROVIDER: PXD029000 | iProX | Fri Oct 08 00:00:00 BST 2021

REPOSITORIES: iProX