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Proteomics dataset of COVID-19 and control patients

ABSTRACT: Proteomics dataset of COVID-19 and control patients

ORGANISM(S): Homo Sapiens

SUBMITTER: Guanghui Liu

PROVIDER: PXD029023 | iProX | Thu Oct 14 00:00:00 BST 2021

REPOSITORIES: iProX

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A single-cell transcriptomic landscape of the lungs of patients with COVID-19.

Wang Si S Yao Xiaohong X Ma Shuai S Ping Yifang Y Fan Yanling Y Sun Shuhui S He Zhicheng Z Shi Yu Y Sun Liang L Xiao Shiqi S Song Moshi M Cai Jun J Li Jiaming J Tang Rui R Zhao Liyun L Wang Chaofu C Wang Qiaoran Q Zhao Lei L Hu Huifang H Liu Xindong X Sun Guoqiang G Chen Lu L Pan Guoqing G Chen Huaiyong H Li Qingrui Q Zhang Peipei P Xu Yuanyuan Y Feng Huyi H Zhao Guo-Guang GG Wen Tianzi T Yang Yungui Y Huang Xuequan X Li Wei W Liu Zhenhua Z Wang Hongmei H Wu Haibo H Hu Baoyang B Ren Yong Y Zhou Qi Q Qu Jing J Zhang Weiqi W Liu Guang-Hui GH Bian Xiu-Wu XW

Nature cell biology 20211207 12

The lung is the primary organ targeted by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), making respiratory failure a leading coronavirus disease 2019 (COVID-19)-related mortality. However, our cellular and molecular understanding of how SARS-CoV-2 infection drives lung pathology is limited. Here we constructed multi-omics and single-nucleus transcriptomic atlases of the lungs of patients with COVID-19, which integrate histological, transcriptomic and proteomic analyses. Our work ...[more]

PMID: 34876692

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