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The proteomic raw data of livers of Takifugu obscurus under hypoxia or (and) infection of Vibrio parahaemolyticus

ABSTRACT: Takifugu obscurus was challenged by V. parahaemolyticus or (and) exposed to hypoxia. The effects of hypoxia and infection of V. parahaemolyticus were identified based on differential metabolites and proteins identified by methods of comparative metabolomics and proteomics on whole livers.

ORGANISM(S): Takifugu Obscurus

SUBMITTER: Yong Zhang

PROVIDER: PXD029027 | iProX | Mon Oct 11 00:00:00 BST 2021

REPOSITORIES: iProX

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Comparative Metabolomics and Proteomics Reveal Vibrio parahaemolyticus Targets Hypoxia-Related Signaling Pathways of Takifugu obscurus.

Xu Jiachang J Yu Xue X Ye Hangyu H Gao Songze S Deng Niuniu N Lu Yuyou Y Lin Haoran H Zhang Yong Y Lu Danqi D

Frontiers in immunology 20220113

Coronavirus disease 2019 (COVID-19) raises the issue of how hypoxia destroys normal physiological function and host immunity against pathogens. However, there are few or no comprehensive omics studies on this effect. From an evolutionary perspective, animals living in complex and changeable marine environments might develop signaling pathways to address bacterial threats under hypoxia. In this study, the ancient genomic model animal Takifugu obscurus and widespread Vibrio parahaemolyti ...[more]

PMID: 35095928

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