Reaction-based fluorogenic probes for selective detection of cysteinyl oxidation in living cells

ABSTRACT: Measuring reactive oxygen, nitrogen and sulfur species in cells is established technology, but turn-on fluorescence tools for detecting the products of their reaction with protein cysteines remain essentially unknown. Toward this goal, here we describe fluorogenic probes for sulfenic acid, a redox modification of protein cysteines inextricably linked to signaling and oxidative stress.

ORGANISM(S): Homo Sapiens

SUBMITTER: Jing Yang  

PROVIDER: PXD029176 | iProX | Mon Oct 18 00:00:00 BST 2021

REPOSITORIES: iProX