Proteomics

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Proteomics of avian pathogenic Escherichia coli ETT2 deletion strain and wild-type strain cultured in serum

ABSTRACT: We use proteomics to explore the factors through which ETT2 affects the serum resistance phenotype of APEC.

ORGANISM(S): Escherichia Coli

SUBMITTER: Kezong Qi  

PROVIDER: PXD029276 | iProX | Fri Oct 22 00:00:00 GMT+01:00 2021

REPOSITORIES: iProX

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The ETT2 transcriptional regulator EivF affects the serum resistance and pathogenicity of avian pathogenic Escherichia coli.

Fu Dandan D   Li Jiaxuan J   Wu Jianmei J   Shao Ying Y   Song Xiangjun X   Tu Jian J   Qi Kezong K  

Microbial pathogenesis 20211025 Pt A

Avian pathogenic Escherichia coli (APEC), a pathotype of extraintestinal pathogenic Escherichia coli (ExPEC), can cause serious systemic infectious diseases in poultry. Escherichia coli type III secretion system 2 (ETT2) is widely distributed in E. coli strains, including ExPEC and Enterohemorrhagic Escherichia coli (EHEC). The transcriptional regulator EivF, which is located at the ETT2 cluster, affects the secretion of LEE-encoded proteins and increases bacterial adhesion to human intestinal e  ...[more]

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