Ontology highlight
ABSTRACT:
ORGANISM(S): Mus Musculus
SUBMITTER: Jing Liu
PROVIDER: PXD029277 | iProX | Fri Oct 22 00:00:00 BST 2021
REPOSITORIES: iProX
Lin Runxia R Zhai Ziwei Z Kuang Junqi J Wu Chuman C Yao Yuxiang Y Shi Ruona R He Jiangping J Xu Shuyang S Li Pengli P Fan Yixin Y Li Wei W Wu Zichao Z Li Xiaoxi X Ming Jin J Guo Jing J Wang Bo B Li Dongwei D Cao Shangtao S Zhang Xiaofei X Li Yi Y Pei Duanqing D Liu Jing J
Cell & bioscience 20220616 1
<h4>Background</h4>The exit from pluripotency or pluripotent-somatic transition (PST) landmarks an event of early mammalian embryonic development, representing a model for cell fate transition.<h4>Results</h4>In this study, using a robust JUN-induced PST within 8 h as a model, we investigate the chromatin accessibility dynamics (CAD) as well as the behaviors of corresponding chromatin remodeling complex SS18/BAFs, to probe the key events at the early stage of PST. Here, we report that, JUN trigg ...[more]