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Discovery of Metal-binding Proteins by METAL-TPP with TPEN

ABSTRACT: Here we developed a chemoproteomic method named METAL-TPP for global discovery of MBPs in proteomes, which operates by extracting metals from MBPs with chelators and logging the resulting structural perturbation of MBPs with thermal proteome profiling.

ORGANISM(S): Homo Sapiens

SUBMITTER: Chu Wang

PROVIDER: PXD029856 | iProX | Sat Nov 20 00:00:00 GMT 2021

REPOSITORIES: iProX

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Discovery of metal-binding proteins by thermal proteome profiling.

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