Requirement of Rbx1 Cullin-RING ligase E3 and Ube2m neddylation E2 in the maintenance of the fitness of Treg cells

ABSTRACT: the Ube2m-Rbx1 axis is required for the maintenance of homeostasis and functions of Treg cells; and Rbx1 has Ube2m-independent roles in the fitness of Treg cells, suggesting a layer of complexity in neddylation activation of CRLs.

ORGANISM(S): Mus Musculus

SUBMITTER: Yi Sun  

PROVIDER: PXD030144 | iProX | Fri Dec 03 00:00:00 GMT 2021

REPOSITORIES: iProX