Induction of antiviral RNA interference by alphaviruses in mammalian somatic cells and adult mice

ABSTRACT: We aimed to examine if vsiSFV possesses any antivirus-independent function. It is possible that vsiSFV might target and degrade the specific host genes during SFV4 infection. To test this, we transfected 293T cells with mimics of vsiSFV (siSFV, 100 nM) or nonspecific siRNA (siNC, 100 nM) for 24 h and sent to LC-MS/MS to screen its potential targets

ORGANISM(S): Homo Sapiens

SUBMITTER: Xi Zhou  

PROVIDER: PXD030194 | iProX | Fri Dec 03 00:00:00 GMT 2021

REPOSITORIES: iProX