Proteomics

Dataset Information

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Lung proteome sequencing of Tibetan sheep


ABSTRACT: To reveal the protein expression patterns in Tibetan sheep lungs at different altitudes, proteome sequencing was performed in this study.

ORGANISM(S): Ovis Aries

SUBMITTER: Yuzhu Luo  

PROVIDER: PXD030661 | iProX | Thu Dec 30 00:00:00 GMT 2021

REPOSITORIES: iProX

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Publications

Physiology and Proteomic Basis of Lung Adaptation to High-Altitude Hypoxia in Tibetan Sheep.

Zhao Pengfei P   Li Shaobin S   He Zhaohua Z   Zhao Fangfang F   Wang Jiqing J   Liu Xiu X   Li Mingna M   Hu Jiang J   Zhao Zhidong Z   Luo Yuzhu Y  

Animals : an open access journal from MDPI 20220819 16


The Tibetan sheep is an indigenous animal of the Tibetan plateau, and after a long period of adaptation have adapted to high-altitude hypoxia. Many physiological changes occur in Tibetan sheep as they adapt to high-altitude hypoxia, especially in the lungs. To reveal the physiological changes and their molecular mechanisms in the lungs of Tibetan sheep during adaptation to high altitudes, we selected Tibetan sheep from three altitudes (2500 m, 3500 m, and 4500 m) and measured blood-gas indicator  ...[more]

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