Soluble TREM2 inhibits secondary nucleation of Aβ fibrillization and enhances cellular uptake of fibrillar Aβ

ABSTRACT: We used sTREM2 obtained from bacterial expression system to form a complex with Aβ40 fibrils in vitro. This complex was chemically cross-linked using two cross-linkers, BS3 and NHSF.

ORGANISM(S): Escherichia Coli

SUBMITTER: Bill DeGrado  

PROVIDER: PXD030722 | iProX | Wed Jan 05 00:00:00 GMT 2022

REPOSITORIES: iProX