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Proteomic landscape of intestinal epithelial cell-derived exosomes in mice

ABSTRACT: Unravelling the proteomic landscape of intestinal epithelial cell-derived exosomes in mice

ORGANISM(S): Mus Musculus

SUBMITTER: Zhenyu Ding

PROVIDER: PXD030945 | iProX | Thu Jan 13 00:00:00 GMT 2022

REPOSITORIES: iProX

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Unraveling the Proteomic Landscape of Intestinal Epithelial Cell-Derived Exosomes in Mice.

Ding Zhenyu Z Zhang Cuiyu C Zhang Baokun B Li Qin Q

Frontiers in physiology 20220223

<h4>Purpose</h4>This study aimed to identify the biological functions of small intestine intestinal epithelial cell derived exosomes (IEC-Exos) and further distinguished the difference proteins in IEC-Exos between ileum and jejunum related to function of the digestive system and occurrence of several diseases.<h4>Materials and methods</h4>IECs of Male C57BL/6J mice were isolated. IEC-Exos were extracted from jejunum and ileum epithelial cell culture fluid by ultracentrifugation. In addition, iso ...[more]

PMID: 35283765

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