Mass spectrometry to exam noval receptors of the The Omicron Variant of SARS-CoV-2 RBD captured by SPIDER

ABSTRACT: We used SPIDER to examine the cell-surface receptors for specific ligands while these receptors were in their native membranes within intact cells in culture. Here we coupled the SPIDER assay with biotinylated RBD of the Omicron Variant of SARS-CoV-2 and biotinylated RBD of SARS-CoV-2. Then we performed mass spectrometry strategy to identify novel binding proteins on the surface of VERO E6,Calu-3,and H1299 cells.

ORGANISM(S): Homo Sapiens Chlorocebus Sabaeus

SUBMITTER: Shengce Tao  

PROVIDER: PXD031035 | iProX | Tue Jan 18 00:00:00 GMT 2022

REPOSITORIES: iProX