Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: Huimin Xia
PROVIDER: PXD031472 | iProX | Mon Feb 07 00:00:00 GMT 2022
REPOSITORIES: iProX
Fang Dajun D Fang Yan Y Zhang Weiqiang W Xiang Yun Y Cheng Xi X Liang Mingfeng M Xia Huimin H
Frontiers in cell and developmental biology 20220722
<b>Background:</b> Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific complication characterized by pruritus without skin damage and jaundice. The poor perinatal outcomes include fetal distress, preterm birth, and unexpected intrauterine death. However, the mechanism of ICP leading to poor prognosis is still unclear. <b>Methods:</b> We analyzed 10 ICP and 10 normal placental specimens through quantitative proteomics of data-independent acquisition (DIA) to screen and identify di ...[more]