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TMT-based proteomic analysis reveals integrins involved in the synergistic infection of reticuloendotheliosis virus and avian leukosis virus subgroup J

ABSTRACT: Comparative analysis of proteome proflings of ALV-J and REV infected and coinfected CEF cells were conducted in this project. We believe this manuscript is valuable for all the researchers who are interested in coinfection with ALV-J and REV.

ORGANISM(S): Gallus Gallus

SUBMITTER: Ziqiang Cheng

PROVIDER: PXD031503 | iProX | Wed Feb 09 00:00:00 GMT 2022

REPOSITORIES: iProX

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TMT-based proteomic analysis reveals integrins involved in the synergistic infection of reticuloendotheliosis virus and avian leukosis virus subgroup J.

Cui Xiyao X Zhang Xinyue X Xue Jingwen J Yao Yongxiu Y Zhou Defang D Cheng Ziqiang Z

BMC veterinary research 20220404 1

<h4>Background</h4>Co-infection with the avian leukosis virus subgroup J (ALV-J) and the reticuloendotheliosis virus (REV) increases mutual viral replication, causing a more serious pathogenic effect by accelerating the progression of neoplasia and extending the tumor spectrum. However, the molecular mechanism underlying the synergistic replication of ALV-J and REV remains unclear.<h4>Results</h4>Here, we performed this study to compare the differentially expressed proteins among CEF cells infec ...[more]

PMID: 35379256

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