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Depression mice primary visual cortex proteome

ABSTRACT: The project included proteomic data sets generated from samples of primary visual cortex of depressed mice and depressed mice receiving c-MSS physical therapy.

ORGANISM(S): Mus Musculus

SUBMITTER: Fangfang Wu

PROVIDER: PXD031598 | iProX | Fri Feb 11 00:00:00 GMT 2022

REPOSITORIES: iProX

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Selective activation of ABCA1/ApoA1 signaling in the V1 by magnetoelectric stimulation ameliorates depression via regulation of synaptic plasticity.

Lu Qingbo Q Wu Fangfang F Jiao Jiao J Xue Le L Song Ruize R Shi Yachen Y Kong Yan Y Sun Jianfei J Gu Ning N Han Ming-Hu MH Zhang Zhijun Z

iScience 20220404 5

Emerging evidence suggests that dysfunction of the visual cortex may be involved in major depressive disorder (MDD). However, the underlying mechanisms remain unclear. We previously established that combined magnetic stimulation system treatment (c-MSST) resulted in an antidepressant effect in mice. In the present study, we found that V1-targeted c-MSST induced significant antidepressant effects in chronic unpredictable mild stress (CUMS)- and lipopolysaccharide (LPS)-treated mice. Proteomic scr ...[more]

PMID: 35479414

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