Proteomics

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Mechanisms research on Huangqin Tang interference with colitis associated colorectal cancer


ABSTRACT: Although the exact molecular mechanisms of colitis associated col orectal cancer are not fully understood, the chronic inflammation positively correlated with tumorigenesis. The Traditional Chinese Medicine botanical formulation Huangqin Tang has significant anti-inflammatory effects. We investigated whether HQT can ameliorate the progression of inflammation to cancer through its anti-inflammatory effects by using relevant predictions and experiments.

ORGANISM(S): Mus Musculus

SUBMITTER: Weipeng Yang  

PROVIDER: PXD031696 | iProX | Wed Feb 16 00:00:00 GMT 2022

REPOSITORIES: iProX

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Publications

Huangqin Tang Interference With Colitis Associated Colorectal Cancer Through Regulation of Epithelial Mesenchymal Transition and Cell Cycle.

Ma Xuran X   Wang Dunfang D   Feng Xue X   Liu Yaqing Y   Li Jia J   Yang Weipeng W  

Frontiers in pharmacology 20220406


<b>Background:</b> Although the exact molecular mechanisms of colitis-associated colorectal cancer are not fully understood, the chronic inflammation was positively correlated with tumorigenesis. The traditional Chinese medicine botanical formulation Huangqin Tang has significant anti-inflammatory effects. We investigated whether HQT can ameliorate the progression of inflammation to cancer through its anti-inflammatory effects by using relevant predictions and experiments. <b>Methods:</b> We use  ...[more]

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