Proteomics of Macrophages：evaluated whether polydatin, the active ingredient in grapes and wine, can repair damaged cells
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus <genus>
SUBMITTER: 
Lanqing Ma
PROVIDER: PXD031839 | iProX | Tue Feb 22 00:00:00 GMT 2022
REPOSITORIES: iProX
Publications
Protective Effects of Polydatin from Grapes and <i>Reynoutria japonica</i> Houtt. on Damaged Macrophages Treated with Acetaminophen.
Liu Can C Wang Wenyi W Zhang Kaixin K Liu Qiudi Q Ma Tongyao T Tan Li L Ma Lanqing L
Nutrients 20220516 10
The unregulated use of acetaminophen (APAP), an antipyretic and analgesic drug, harms hepatocytes and kidney cells, leading to liver failure and acute kidney injury. Herein, we investigate whether APAP damages macrophages in the immune system by observing its effects on macrophage proliferation and apoptosis. Using proteomics, we analyzed the effects of APAP on macrophage protein expression profiles and evaluated whether polydatin, the active ingredient in grapes and wine, can repair the damaged ...[more]
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