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Mass spectrometry with DIA quantification of cerebrospinal fluid in 20 subarachnoid hemorrhage patients

ABSTRACT: We applied mass spectrometry with DIA quantification to identify biomarker candidates in CSF samples from a well-characterized cohort consisted of 20 SAH patients.

ORGANISM(S): Human Csf-associated Densovirus

SUBMITTER: Songtao Qi

PROVIDER: PXD032118 | iProX | Tue Mar 08 00:00:00 GMT 2022

REPOSITORIES: iProX

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Transcriptomic Analysis Reveals that Activating Transcription Factor 3/c-Jun/Lgals3 Axis Is Associated with Central Diabetes Insipidus after Hypothalamic Injury.

Zhou Mingfeng M Ou Yichao Y Wu Guangsen G Li Kai K Peng Junjie J Wang Xingqin X Che Mengjie M Gong Haodong H Niu Peirong P Liu Yawei Y Feng Zhanpeng Z Qi Songtao S

Neuroendocrinology 20211111 9

<h4>Background</h4>Hypothalamic injury causes several complicated neuroendocrine-associated disorders, such as water-electrolyte imbalance, obesity, and hypopituitarism. Among these, central diabetes insipidus (CDI), characterized by polyuria, polydipsia, low urine specific gravity, and deficiency of arginine vasopressin contents, is a typical complication after hypothalamic injury.<h4>Methods</h4>CDI was induced by hypothalamic pituitary stalk injury in male animals. Behavioral parameters and b ...[more]

PMID: 34763342

Publication: 1/2

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