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Hierarchical Helical Carbon Nanotube Fibre as a Bone Integrating ACL Replacement

ABSTRACT: Hierarchically assembled helical fiber integrates effectively with bones

ORGANISM(S): Oryctolagus Cuniculus Homo Sapiens

SUBMITTER: Jiajun Zhu

PROVIDER: PXD032128 | iProX | Fri Mar 17 00:00:00 GMT 2023

REPOSITORIES: iProX

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Hierarchical helical carbon nanotube fibre as a bone-integrating anterior cruciate ligament replacement.

Wang Liyuan L Wan Fang F Xu Yifan Y Xie Songlin S Zhao Tiancheng T Zhang Fan F Yang Han H Zhu Jiajun J Gao Jingming J Shi Xiang X Wang Chuang C Lu Linwei L Yang Yifan Y Yu Xiaoye X Chen Shiyi S Sun Xuemei X Ding Jiandong J Chen Peining P Ding Chen C Xu Fan F Yu Hongbo H Peng Huisheng H

Nature nanotechnology 20230504 9

High rates of ligament damage require replacements; however, current synthetic materials have issues with bone integration leading to implant failure. Here we introduce an artificial ligament that has the required mechanical properties and can integrate with the host bone and restore movement in animals. The ligament is assembled from aligned carbon nanotubes formed into hierarchical helical fibres bearing nanometre and micrometre channels. Osseointegration of the artificial ligament is observed ...[more]

PMID: 37142709

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