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Proteomics data of WHO I and WHO III meningiomas

ABSTRACT: Proteomics data of endothelial meningiomas, fibrous meningiomas and anaplastic meningiomas

ORGANISM(S): Homo Sapiens

SUBMITTER: Jie Feng

PROVIDER: PXD032342 | iProX | Thu Mar 17 00:00:00 GMT 2022

REPOSITORIES: iProX

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A Nicotinamide Phosphoribosyltransferase Inhibitor, FK866, Suppresses the Growth of Anaplastic Meningiomas and Inhibits Immune Checkpoint Expression by Regulating STAT1.

Deng Yuxuan Y Hu Boyi B Miao Yazhou Y Wang Jing J Zhang Shaodong S Wan Hong H Wu Zhen Z Lv Yifan Y Feng Jie J Ji Nan N Park Deric D Hao Shuyu S

Frontiers in oncology 20220420

Anaplastic meningioma is classified as a World Health Organization (WHO) grade III tumor and shows a strong tendency to recur. Although the incidence of anaplastic meningioma is low, the high rate of recurrence and death still makes treatment a challenge. A proteomics analysis was performed to investigate the differentially expressed proteins between anaplastic meningiomas and fibrous meningiomas by micro-LC-MS/MS. The key metabolic enzyme nicotinamide phosphoribosyltransferase (NAMPT) showed up ...[more]

PMID: 35515130

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