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Quantitative Proteomics Analysis of Exosomes

ABSTRACT: Comparing the proteomic data within Salmonella infected and non-infected group exosomes,then analysis the role of SopB played in immune modulation

ORGANISM(S): Homo Sapiens

SUBMITTER: Haihua Ruan

PROVIDER: PXD032776 | iProX | Wed Mar 23 00:00:00 GMT 2022

REPOSITORIES: iProX

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Label-free relative quantitative proteomics reveals extracellular vesicles as a vehicle for Salmonella effector protein delivery.

Wu Tao T Zhang Biao B Lu Juane J Huang Ailin A Wu Hao H Qiao Jianjun J Ruan Haihua H

Frontiers in microbiology 20221215

Extracellular vesicles are small vesicles with a diameter of 30-150 nm that are actively secreted by eukaryotic cells and play important roles in intercellular communication, immune responses, and tumorigenesis. Previous studies have shown that extracellular vesicles are involved in the process of Salmonella enterica serovar Typhimurium (S. Typhimurium) infection. However, changes in the protein content of extracellular vesicles elicited by S. Typhimurium infection have not ...[more]

PMID: 36590436

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