Polygonum perfoliatum L. ameliorates NAFLD by promoting PPARs/CPT1A/CPT2-mediated fatty acid β-oxidation
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus Musculus
SUBMITTER: 
Xiaoni Kong
PROVIDER: PXD033219 | iProX | Mon Feb 05 00:00:00 GMT 2024
REPOSITORIES: iProX
Publications
Quantitative proteomics reveals <i>Polygonum perfoliatum L.</i> ameliorates hepatic steatosis by promoting PPARs/CPT1A/CPT2-mediated fatty acid β-oxidation.
Liu Guanjie G Chang Ling L Qian Yihan Y Lin Jiacheng J Shang Zhi Z Xu Min M Wang Fang F Sun Xuehua X Jiang Yun Y Gao Yueqiu Y Kong Xiaoni X
Frontiers in pharmacology 20230323
Non-alcoholic fatty liver disease (NAFLD) is a predominant contributor to end-stage liver disease in the forthcoming decades. <i>Polygonum perfoliatum L.</i> (PPL) is an herbal medicine with anti-lipid peroxidation and anti-inflammatory properties. However, detailed hepatoprotective effects of PPL against NAFLD and its underlying mechanisms are not fully understood. Here, we found that PPL protects against high fat diet (HFD)-induced hepatic steatosis, lipid peroxidation, and glucose-lipid metab ...[more]
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To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource
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To cite BioModels Database, please use: BioModels Database: An enhanced, curated and annotated resource
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To the extent possible under law, all copyright and related or
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