Proteomics

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Validation of Serotransferrin in the Serum as Candidate Biomarkers for the Diagnose of Pulmonary Tuberculosis by Label-free LC/MS


ABSTRACT: Label-free LC/MS profiles of neutrophils from 15 active TB patients and 15 healthy controls

ORGANISM(S): Homo Sapiens

SUBMITTER: Junming Li  

PROVIDER: PXD033563 | iProX | Thu Apr 28 00:00:00 BST 2022

REPOSITORIES: iProX

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Validation of Serotransferrin in the Serum as Candidate Biomarkers for the Diagnosis of Pulmonary Tuberculosis by Label-Free LC/MS.

Li Xue X   Gao Yujie Y   Liu Jun J   Xujian Qing Q   Luo Qing Q   Huang Zikun Z   Li Junming J  

ACS omega 20220706 28


This study aimed to identify secreted protein biomarkers in serum from the label-free LC/MS proteomics of neutrophils in pulmonary tuberculosis (TB) patients for the diagnosis biomarkers of TB label-free LC/MS. The proteomic profiles of neutrophils from 15 active TB patients and 15 healthy controls (HCs) were analyzed using label-free LC/MS. We identified 358 differentially expressed proteins preliminarily, including 279 up-regulated proteins and 79 down-regulated proteins. Thirty-eight differen  ...[more]

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