Characterization of LC-MS based urine metabolomics in healthy children and adults
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Wei Sun
PROVIDER: PXD034390 | iProX | Mon Jun 06 00:00:00 BST 2022
REPOSITORIES: iProX
Publications
Characterization of LC-MS based urine metabolomics in healthy children and adults.
Liu Xiaoyan X Tian Xiaoyi X Qinghong Shi S Sun Haidan H Jing Li L Tang Xiaoyue X Guo Zhengguang Z Liu Ying Y Wang Yan Y Ma Jie J Na Ren R He Chengyan C Song Wenqi W Sun Wei W
PeerJ 20220622
Previous studies reported that sex and age could influence urine metabolomics, which should be considered in biomarker discovery. As a consequence, for the baseline of urine metabolomics characteristics, it becomes critical to avoid confounding effects in clinical cohort studies. In this study, we provided a comprehensive lifespan characterization of urine metabolomics in a cohort of 348 healthy children and 315 adults, aged 1 to 78 years, using liquid chromatography coupled with high resolution ...[more]
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