Proteomics

Dataset Information

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Proteome data of snake venom_file 13


ABSTRACT: Proteome data of venomous snake profiled using liquid chromatography tandem mass spectrometry (LCMS/MS)

ORGANISM(S): Naja Sumatrana

SUBMITTER: Choo Hock Tan  

PROVIDER: PXD034497 | iProX | Tue Jun 14 00:00:00 BST 2022

REPOSITORIES: iProX

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Publications

Equatorial Spitting Cobra (<i>Naja sumatrana</i>) from Malaysia (Negeri Sembilan and Penang), Southern Thailand, and Sumatra: Comparative Venom Proteomics, Immunoreactivity and Cross-Neutralization by Antivenom.

Tan Choo Hock CH   Tan Kae Yi KY   Wong Kin Ying KY   Tan Nget Hong NH   Chong Ho Phin HP  

Toxins 20220729 8


The Equatorial Spitting Cobra (<i>Naja sumatrana</i>) is a medically important venomous snake species in Southeast Asia. Its wide geographical distribution implies potential intra-specific venom variation, while there is no species-specific antivenom available to treat its envenoming. Applying a protein-decomplexing proteomic approach, the study showed that three-finger toxins (3FTX), followed by phospholipases A<sub>2</sub> (PLA<sub>2</sub>), were the major proteins well-conserved across <i>N.  ...[more]

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