Proteomics

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Integrated Proteomics and Metabolomics Analysis in Pregnant Rat Hippocampus After Circadian Rhythm Inversion


ABSTRACT: To investigate the changes in proteins, metabolites, and related mechanisms in the Q7 hypothalamus of pregnant rats after circadian rhythm inversion during the whole pregnancy cycle

ORGANISM(S): Rattus Rattus

SUBMITTER: Rongjin Lin  

PROVIDER: PXD034926 | iProX | Sun Jun 26 00:00:00 BST 2022

REPOSITORIES: iProX

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Integrated Proteomics and Metabolomics Analysis in Pregnant Rat Hippocampus After Circadian Rhythm Inversion.

Lin Jingjing J   Sun Xinyue X   Dai Xiaofeng X   Zhang Shaoying S   Zhang Xueling X   Wang Qiaosong Q   Zheng Qirong Q   Huang Minfang M   He Yuanyuan Y   Lin Rongjin R  

Frontiers in physiology 20220722


To investigate the changes in proteins, metabolites, and related mechanisms in the hypothalamus of pregnant rats after circadian rhythm inversion during the whole pregnancy cycle. A total of 12 Wistar female rats aged 7 weeks were randomly divided into control (six rats) and experimental (six rats) groups at the beginning of pregnancy. The control group followed a 12-h light and dark cycle (6 a.m. to 6 p.m. light, 6 p.m. to 6 a.m. dark the next day), and the experimental group followed a complet  ...[more]

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